Antiretroviral Agents and Prevention of Malaria in HIV-Infected Ugandan Children
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Summary
The authors compared malaria incidence in HIV-infected children on protease inhibitor-based regimens (lopinavir–ritonavir) to those receiving nonnucleoside reverse-transcriptase inhibitor (NNRTI)–based ART. They conclude that lopinavir–ritonavir–based ART as compared with NNRTI-based ART reduced the incidence of malaria by 41 per cent, with the lower incidence attributable largely to a significant reduction in the recurrence of malaria after treatment with artemether–lumefantrine. Lopinavir–ritonavir–based ART was accompanied by an increase in serious adverse events.
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Massachusetts Medical Society |
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English |
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Web Page |
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Global |
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Policymakers, Program Managers, Researchers |
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Opportunistic Infections & Associated Conditions, Primary Care of HIV Infected & Exposed Children, Pediatric Antiretroviral Treatment |
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Journal Articles |
